L-Tyrosine disodium salt (CAS: 69847-45-6) Product Introduction
L-Tyrosine disodium salt, with the CAS number 69847-45-6, is a water-soluble sodium salt derivative of L-tyrosine, also known as Disodium L-tyrosinate or L-Tyrosine disodium. Its molecular formula is C₉H₁₀NNa₂O₃, and its molecular weight is 237.16 g/mol. As a derivative of the essential amino acid L-tyrosine, it overcomes the low water solubility of free L-tyrosine, featuring excellent stability, good biocompatibility, and retained physiological activity, making it widely applied in pharmaceuticals, food, cosmetics, and biochemistry research.
Physically, L-Tyrosine disodium salt appears as a white to off-white crystalline powder or granular solid. It has a melting point of approximately 240℃ (decomposition) and is highly soluble in water, forming a clear and stable aqueous solution, while it is slightly soluble in methanol and ethanol, and insoluble in non-polar solvents. It is optically active, with a specific rotation [α]²⁰/D of -12.0° to -16.0° (in water, c=2). It has low hygroscopicity and remains stable under normal temperature and pressure when stored properly, facilitating easy handling, storage, and formulation.
Chemically, it retains the core structure of L-tyrosine, with two carboxyl groups neutralized to form sodium salts, which significantly enhances its water solubility and bioavailability compared to free L-tyrosine. It contains amino groups, phenolic hydroxyl groups, and sodium carboxylate groups, enabling it to participate in various biochemical reactions. It is stable under neutral and weakly alkaline conditions but may decompose under strong acid or high-temperature environments, and the phenolic hydroxyl group endows it with mild antioxidant activity.
Its core applications cover multiple fields. In the pharmaceutical industry, it serves as a raw material for preparing nutritional supplements, amino acid injections, and drugs for regulating neurotransmitter synthesis, as L-tyrosine is a precursor for dopamine, norepinephrine, and melanin. In biochemistry research, it is used as a biochemical reagent for studying amino acid metabolism, enzyme activity, and protein synthesis, and as an additive in cell culture media.
In the food industry, it acts as a nutritional additive and flavor enhancer, added to health products, functional beverages, and processed foods to replenish essential amino acids and improve taste. In cosmetics, it is added to skin care products to nourish the skin, promote melanin synthesis, and improve skin tone. Safety-wise, it is generally recognized as safe (GRAS), non-toxic and non-irritating under normal handling. It should be stored in a sealed, cool, dry, and dark environment at 2-8℃, away from strong oxidants, moisture, and high temperatures to prevent decomposition and moisture absorption. With its excellent solubility and physiological activity, it is an indispensable raw material in multiple high-value fields.