L-Tyrosine disodium salt (CAS: 122666-87-9) Product Introduction
L-Tyrosine disodium salt, with the CAS number 122666-87-9, is a water-soluble sodium salt derivative of the essential amino acid L-tyrosine, also known as Disodium L-tyrosinate or L-Tyrosine disodium. Its molecular formula is C₉H₁₀NNa₂O₃, and its molecular weight is 237.16 g/mol. As a modified form of L-tyrosine, it effectively overcomes the low water solubility of free L-tyrosine, while retaining its inherent physiological activity, featuring good stability and biocompatibility, making it widely applied in pharmaceuticals, food supplements, cosmetics, and biochemistry research fields.
Physically, L-Tyrosine disodium salt appears as a white to off-white crystalline powder or granular solid. It has a melting point of approximately 240℃ (decomposition) and is highly soluble in water, forming a clear, stable aqueous solution, which greatly facilitates its formulation in various aqueous-based products. It is slightly soluble in methanol and ethanol, and insoluble in non-polar solvents. It is optically active, with a specific rotation [α]²⁰/D of -12.0° to -16.0° (in water, c=2), and has low hygroscopicity, remaining stable under normal temperature and pressure when stored properly, ensuring easy handling, storage, and transportation.
Chemically, it retains the core structure of L-tyrosine, with its carboxyl groups neutralized to form sodium salts—this modification is the key to its enhanced water solubility and bioavailability compared to free L-tyrosine. It contains amino groups, phenolic hydroxyl groups, and sodium carboxylate groups, enabling it to participate in various biochemical reactions. It is stable under neutral and weakly alkaline conditions but may decompose under strong acid or high-temperature environments, and the phenolic hydroxyl group endows it with mild antioxidant activity.
Its core applications span multiple high-value fields. In the pharmaceutical industry, it serves as a raw material for preparing amino acid injections, nutritional supplements, and drugs targeting neurotransmitter synthesis, as L-tyrosine is a precursor for dopamine, norepinephrine, and melanin, supporting neurological health and physiological regulation. In biochemistry research, it is used as a biochemical reagent for studying amino acid metabolism, enzyme activity, and protein synthesis, as well as an additive in cell culture media.
In the food industry, it acts as a nutritional additive, added to health products, functional beverages, and processed foods to replenish essential amino acids. In cosmetics, it is incorporated into skin care products to nourish the skin, promote melanin synthesis, and improve skin tone. Safety-wise, it is generally recognized as safe (GRAS), non-toxic and non-irritating under normal handling. It should be stored in a sealed, cool, dry, and dark environment at 2-8℃, away from strong oxidants, moisture, and high temperatures to prevent decomposition and moisture absorption. With its excellent solubility and retained physiological activity, it is an indispensable raw material in multiple industries.