Water Soluble Orotic Acid Monohydrate White Powder CAS 50887-69-9

Orotic Acid Monohydrate (CAS: 50887-69-9)

    Orotic Acid Monohydrate is a heterocyclic organic compound widely used in biochemical research, pharmaceutical intermediates, and nutritional studies. Chemically known as 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid monohydrate, it belongs to the pyrimidine family and plays a critical role in nucleotide biosynthesis.

    This compound has a molecular formula of C₅H₆N₂O₅ and a molecular weight of approximately 174.11 g/mol. It typically appears as a white to off-white crystalline powder with high thermal stability, exhibiting a melting point above 300 °C. It is slightly soluble in water and certain organic solvents such as DMSO, and demonstrates stable physicochemical properties under standard storage conditions.

    From a biochemical perspective, orotic acid monohydrate is an important intermediate in the de novo synthesis of pyrimidine nucleotides. It is directly involved in the formation of uridine monophosphate (UMP), a key precursor for RNA and DNA synthesis. Due to this role, it is frequently utilized in research related to cell metabolism, genetic material synthesis, and enzymatic pathways.

In the pharmaceutical and nutraceutical industries, this compound is sometimes referred to as a form of “Vitamin B13,” although it is not officially classified as a vitamin. It has been studied for its potential applications in supporting metabolic processes, liver function research, and mineral transport when used in orotate salt forms. Additionally, it serves as a valuable building block in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

    Orotic acid monohydrate is commonly supplied with high purity levels (≥97–99%), making it suitable for laboratory analysis, R&D applications, and industrial synthesis. Standard packaging ranges from gram-scale laboratory quantities to bulk supply for manufacturing purposes.

    In terms of safety, the compound is generally classified as an irritant and should be handled with appropriate protective equipment, including gloves and eye protection. Proper storage in a cool, dry, and well-sealed environment is recommended to maintain product stability and quality.

    Overall, Orotic Acid Monohydrate is a versatile biochemical reagent with significant value in life sciences, pharmaceutical development, and chemical synthesis, offering reliable performance and consistency for both research and industrial applications.