H-Ser(tBu)-NH₂·HCl CAS 323587-47-9 O-tert-Butyl-L-serinamide hydrochloride for Peptide Synthesis

H-Ser(tBu)-NH₂·HCl, also named O-tert-Butyl-L-serinamide hydrochloride, with molecular formula C₇H₁₇ClN₂O₂, molecular weight 196.68, CAS 323587-47-9, PubChem CID 87713751.
It is a L-serine derivative with tert-butyl protecting group on side-chain hydroxyl and C-terminal amide. The tBu group is stable under Fmoc SPPS condition and can be cleaved by acid. It is widely used for synthesis of C-terminal amide peptides, branched peptides and therapeutic peptide candidates.

Key Benefits:

• Side chain OH protected by tert-butyl group for orthogonal deprotection
• Ideal building block for solid phase peptide synthesis (SPPS)
• Stable under standard Fmoc peptide synthesis reaction conditions
• High purity for pharmaceutical & research peptide development

Target Industries: Peptide Synthesis, Pharmaceutical Intermediates, Biochemical Research, Custom Peptide Manufacturing Applications: C-terminal Amide Peptides, Therapeutic Peptides, Biopharmaceutical R&D